Theoretically, humans age throughout their lives, but the first signs of aging are usually noticed after the age of 30. This is when the first wrinkles appear, and many of us have already discovered our first gray hair. However, experts have made a surprising discovery, marking a revolution in understanding aging and explaining the rise of health problems in specific age groups.
At what age do people age the fastest? Scientists identify two "jumps"
A study conducted by scientists from Stanford University involved 108 participants aged 25 to 75. Every few months, they provided blood and stool samples, as well as swabs from their skin, mouth, and nose. Depending on their age, some did this for a year, while others continued for up to seven years. This allowed experts to analyze 135,000 different molecules and microbes. The research revealed two major waves of age-related changes. The first "jump" occurs at age 44, and the second at age 60. Initially, the researchers thought the first wave was related to menopausal changes in women. However, it quickly became clear that similar changes also occur in men.
At what age do people start getting sick? One moment is crucial
The samples collected from the volunteers were linked to the functioning of the immune system, cardiovascular system, metabolism, kidneys, as well as muscle and skin composition. A staggering 81% of molecules did not change continuously but underwent significant transformations in individuals at the ages of 44 and 60. "This study explains why many people suddenly start feeling their age. It challenges the traditional view that aging is a slow, continuous process," said family doctor John Whyte in an interview with nationalgeographic.com.
According to experts, this explains why, after age 40, the body has a harder time processing caffeine and alcohol, cholesterol levels rise, skin becomes looser, and people experience more muscle strains and injuries. In individuals aged 60, even more molecular changes were observed in molecules related to kidney function and the immune system. According to Michael Snyder (co-author of the study), this explains why older adults are more susceptible to diseases such as COVID-19, cancer, and cardiovascular disorders.
